Clinical Therapeutics. Further information: Oophorectomy. When used on females, the effects are similar, though there is little research about chemically lowering female's sex drive or female-specific anaphrodisiacs, since most research focuses on the opposite, but anti-androgenic hormone regimens would lower testosterone in females which can impact sex drive or sexual response.
On June 5,Estonia passed a law that allows voluntary chemical castration as a part of complex treatment for less serious sex offenders as an alternative of imprisonment. Frederick Berlin, who treats patients with sexual disorders at Johns Hopkins Hospital and at an independent clinic.
Grubin D, Beech A.
Forty of those subjects were recorded as to have diminished desires for deviant sexual behaviour, less frequent sexual fantasies, and greater control over sexual urges. Clinical review: Ethical and medical considerations of androgen deprivation treatment of sex offenders. Also seen is a sudden shrinking chemical castration for male sex offenders in Staffordshire bone mass and discoloration of the lips,   reduced body hair,  and muscle mass.
The Alabama law says sex offenders whose crimes involved children between ages 7 and 13 must receive the medication before being released from prison on parole. American Journal of Psychiatry. These scientists argue that these observations, along with the fact that humans are animals and subject to evolutionshow that it is flawed to think that male sexuality would be treatable by medication if female sexuality is not.
Scott CL, Holmberg T.
In , John Money became the first American to employ chemical castration by prescribing medroxyprogesterone acetate MPA, the base ingredient now used in DMPA as a treatment for a patient dealing with pedophilic urges. The American Journal of Surgical Pathology.
At least seven states have laws authorizing chemical castration in some form. The program developers note the voluntary nature of the program a crucial factor in its success.